Sergent-Suicide-Montreal-Gazette-Coverage IDNUMBER 199703210134 BASNUM 2613522 PAPER Montreal Gazette DATE 970321 PDATE Friday, March 21, 1997 EDITION Final SECTION News PAGE A5 LENGTH 387 words LKW UNIVERSITIES; QUEBEC; MCGILL UNIVERSITY; SCIENCE TECHNOLOGY; ETHICS; JUSTINE SERGENT, SUICIDE; 1994 HEADLINE McGill ends 2nd inquiry of Sergent suicide: Estate objected BYLINE JOHN KALBFLEISCH SOURCE The Gazette A hunt for possible scientific fraud in the research of a McGill University scientist who killed herself three years ago has suddenly been shut down by the university. The scientific audit was set up following the April 1994 death of neurological researcher Justine Sergent, who had been accused in an anonymous letter of unethical behavior. McGill sent out a tersely worded notice yesterday about the end of the audit. There will be no report. The Sergent estate has objected to the audit continuing because one of its two members resigned last fall. This means all official inquiries into the matter have been canceled without any public light being shed on Sergent's death or research. Claude-Armand Sheppard, the lawyer for the Sergent estate, said he called for the audit to be canceled because he was unhappy with the way the matter was handled. He said he tried for two months to find out why Pierre Bois resigned from the audit. The former dean of medicine at Universite de Montreal quit on Oct. 26 for health reasons. That left only Marcus Raichle, a neurologist at Washington University in St. Louis. "It's not that we were challenging Raichle's competence," Sheppard said in an interview. "But transparency demanded a two-man inquiry. The rules were changed without us being told. Don't try to tell me that an inquiry done by one person is as good as one done by two.,. He said the estate had agreed with McGill on Jan. 15 to wind up a second inquiry - into disciplinary measures launched against Sergent and other difficulties she faced at the university - on the understanding that the scientific audit would proceed. Yet it was only in The Gazette's report of that development, he said, that the estate learned of the resignation. The January agreement, he said, "contemplated a two-person committee headed by Dr. Bois." He said the process had become hopelessly flawed, and accused McGill of being "not serious - if it ever was - about the audit and about protecting the scientific reputation of Dr. Justine Sergent. Sergent and her husband committed suicide several days after a Gazette article reported about the anonymous letter and of administrative disputes over her failure to get proper authorization for certain experiments. But McGill was quoted saying there was no fraud in the case. DOE 19970321 UPDATE 970321 NDATE 19970321 NUPDATE 19970321 ========== END OF DOCUMENT ========== IDNUMBER 199701160201 BASNUM 2581510 PAPER Montreal Gazette DATE 970116 PDATE Thursday, January 16, 1997 EDITION Final SECTION News PAGE A3 LENGTH 512 words LKW UNIVERSITIES; MONTREAL; MCGILL, UNIVERSITY; SCIENCE & TECHNOLOGY; DISCIPLINARY ACTIONS; JUSTINE SERGENT ; SUICIDE; LAWSUITS HEADLINE McGill, estate for researcher end hostilities BYLINE JOHN KALBFLEISCH SOURCE The Gazette McGill University and the estate of neurology researcher Justine Sergent, wearied by years of confrontation, have laid down their arms. Citing the passage of time and the mounting expense of litigation, McGill has agreed to end its inquiry into disciplinary measures the university had launched against Sergent, as well as into other aspects of her career there. For its part, the Sergent estate is dropping its assertion before the courts that McGill's inquiry was inherently flawed because of the university's involvement in the affair. Sergent, of the McGill-affiliated Montreal Neurological Institute, was recognized as a world leader in cognitive neuroscience. In April 1994, she committed suicide in her north-end home, to be followed several hours later by her husband. She was 42. It was the extraordinary climax to a series of events that began with an internal complaint in July 1992 about some experiments on brain functioning that she was conducting. - In January 1993, McGill reprimanded Sergent for conducting the experiments without proper ethics-committee approval, even though her volunteer subjects had given their informed consent. At no time was the subjects' safety or the soundness of Sergent's scientific procedures in question. Sergent appealed, and the case went to arbitration. - In April 1994, The Gazette, among others, received an anonymous letter implying scientific fraud by Sergent. In a Gazette story April 9 that described McGill's reprimand, university officials and Sergent alike dismissed the allegation of fraud. Sergent told The Gazette that she herself had invited a scientific audit of her work. The article represented the first time the affair was widely publicized. - In a suicide note dated April 10, Sergent wrote that the Gazette story blew her troubles with McGill out of proportion and threw "discredit on myself, my work and my career, which I cannot tolerate." Two days later, she and her husband were found dead of carbon-monoxide poisoning. - Later that month, McGill set up its inquiry. It also commissioned Pierre Bois, a former dean of medicine at the Universite de Montreal, and neurologist Marcus Raichle of Washington University in St. Louis to conduct a scientific audit of Sergent's work. Almost from the outset, the first McGill inquiry, led by Montreal lawyer Caspar Bloom, was hobbled by wrangling. Sergent's estate complained that Bloom was compromised because the university itself had commissioned him to investigate its actions. The estate won an injunction suspending Bloom's inquiry, and the protracted manoeuvring that followed failed to get the process started again. Yesterday's settlement affirms that Bloom acted competently and objectively. The settlement does not affect the scientific audit (from which Bois has withdrawn, for private reasons). Yesterday, Richard Murphy, the Neuro's director, acknowledged that questions will always remain in the mind of the public about what happened between McGill and Sergent. "But knowing what I know," he said, "I am confident that if the Bloom inquiry had been allowed to continue, it would have shown that McGill acted properly. It was a tragedy to lose her and her husband. "But I agree that the time has come to close this unfortunate chapter." DOB UPDATE NDATE NUPDATE 19970116 970116 19970116 19970116 ========== END OF DOCUMENT ========== BASNUM 2094095 PAPER Montreal Gazette DATE 941124 PDATE Thursday, November 24, 1994 EDITION Final SECTION News PAGE A4 LENGTH 842 words LKW SUICIDE LETTER MCGILL UNIVERSITY HEADLINE No end to our nightmare in sight, suicide note says BYLINE JUSTINE SERGENT SOURCE (Freelance) Following is the text of the suicide note written by McGill University researcher Justine Sergent: When you read this letter, I will be dead. My husband and I have chosen to retire from life, as we can no longer bear the nightmare that our lives have been for more than two years. The publication in Saturday's Gazette (April 9) of an article, triggered by an anonymous letter, suggests that we cannot expect any improvement in our current situation and, if newspapers are ready to take anonymous and unsubstantiated accusations seriously, there is no end to our nightmare in sight. I have been accused of breaking rules. The ethics committee of the Montreal Neurological Institute (MI) considered that I did not abide by the rules because I carried out a study on reading musical notation with positron emission tomography (PET). Because similar studies requiring subjects to look at faces or to read letters or words with the same technology (PET) had been approved, I did not consider putting subjects at more risk by exposing them to a different type of visual information. In addition, the ethics committee itself is not competent to decide as to whether or not I broke the rule because it does not abide by the guidelines of the Medical Research Council (MRC) of Canada. According to these guidelines, at least one expert in my research either cognitive neuroscience or positron emission tomography, should have sat on the committee evaluating my research, but no expert in neuropsychology, nuclear medicine, or positron emission tomography was a member of the ethics committee in this evaluation. I have also been accused of altering the telephone numbers of some subjects. I did admit doing this for the following reasons. The consent forms signed by the subjects stipulate that everything about the participation in a study is confidential. Yet, I had received complaints from subjects participating in earlier studies that someone, claiming to be either from "security at McGill" or from the "director's office" was calling them and asking them questions about the various tasks they had been performing during my PET studies. I therefore decided to ensure the confidentiality of the subjects by altering the telephone number on the official form, which I did in their presence, while keeping the correct number in my files. Although I mentioned this to the chairman of my department, my subjects were still being called six months later. In the context these events took place, I then thought these were the best way of acting. The university thinks differently, and we are therefore in arbitration about this. This, however, did not have to be exposed in a newspaper and blown out of proportion, and it allows a discredit on myself, my work and my career, which I cannot tolerate. Before seeing this article, I had hoped that having my research data being investigated and audited would at least clear my name, as the anonymous letter raises doubts about my honesty as a scientist. I love research too much to even consider tampering with data or making false claims, and anyone working in my research field or participating in my experiments could testify that I have always paid much attention to the quality and rigor of my studies and to the welfare of the subjects or patients participating in them. Unfortunately, I cannot even have the assurance that the MI and its director would proceed fairly and honestly. No later than 10 days ago, I found out, by accident, that the director of the MI had withheld information which I had sent to him for promotion consideration, and had not forwarded this information to the members of the committee responsible for evaluating my dossier. He instead sent to the committee a curriculum vitae different from the one I had submitted for promotion consideration and that comprised only six lines on my teaching activities compared to three pages and a half in the curriculum vitae I had sent for promotion consideration. As a result of the missing information, I was denied promotion. Although this looks like falsification of information, (I) just received a letter from the director whereby he finds nothing wrong with what he did and justifies his action by putting the blame on me for not updating the information when I was given the opportunity, but I had no significantly new information to update. This attitude reflects my work situation during the last two years and a half which has consisted of a continuing form of harassment which recent events suggest are likely to be getting worse. I was a young, successful, woman scientist, and this may not be welcome attributes in the scientific world or at least in the mind of some people. I had a rich and intense life, but there comes a point when one can no longer fight and one needs a rest. It is this rest that my husband, who has supported me in all aspects of my activities and my life, and myself have decide to take. Montreal, April 10, 1994 * Justine Sergent DOB 19941125 UPDATE 960708 NDATE 19941124 NUPDATE 19960708 ========== END OF DOCUMENT ========== IDNUMBER 199407120028 BASNUM 2026528 PAPER Montreal Gazette DATE 940712 PDATE Tuesday, July 12, 1994 EDITION Final SECTION News PAGE Al/FRONT LENGTH 512 words LKW MEDICAL RESEARCH ETHICS MCGILL UNIVERSITY SUICIDE HEADLINE Sergents died separately, note indicates BYLINE CAROLYN ADOLPH SOURCE GAZETTE A letter written by the husband of McGill University researcher Justine Sergent indicates that when the two committed suicide in April, they may have ended their lives separately. "It is 3:30 a.m. on April 11, Justine is dead, and it will soon be my turn," says the letter, written by Yves Sergent and quoted from in the coroner's report. "I've just spent the most horrible hours of my life, seeing to the fulfilment of Justine's last wish." The letter concluded, "My hour has come, I will join Justine for ever and I hope this attempt does not fail." The Sergents committed suicide two days after The Gazette reported that Justine Sergent had been disciplined for failing to get ethics-committee approval for some of her experiments and was appealing the reprimand. Despite Yves Sergent's letter, coroner Teresa Sourour listed the official time of death as 11:40 a.m. on April 12, That was when they were pronounced dead, shortly after both bodies were found by police. The report was completed June 22 and was recently released. A spokesman for the coroner's office, Francois Houle, said Sourour was unable to establish the exact time of death from examination of the bodies. Justine and Yves Sergent died of carbon monoxide poisoning in their car, and levels of the substance in their bodies were roughly the same. "It's impossible to tell who died first and when, but the difference in hours cannot be great - a few hours," said Houle. Letters left by the couple indicate that publication of the disciplinary action had a "devastating effect." Letters written April 10 indicate that Sergent "could not tolerate what she believed to be public humiliation and an attack on her personal and professional credibility," Sourour said. Both complained of the "odious anonymous letter" which sparked the newspaper story, Sourour said. The coroner also stated that The Gazette published this anonymous letter. However, the letter was not published: the newspaper reported on the official reprimand and published Sergent's comments on the matter. Justine and Yves Sergent were found April 12 lying in their car, which was parked in the garage of their home. Both had taken sedatives before their deaths, and there were knife slashes on Yves Sergent's neck and the insides of his elbows. Sourour said the cuts were probably self-inflicted. However, none of the cuts pierced the main veins or arteries, and they were not the cause of death. Two knives were found on the dashboard in front of the driver's seat, where Yves Sergent's body was found. Justine Sergent's body was in the front passenger's seat. McGill University is proceeding with an independent investigation of the tragedy, led by lawyer Casper Bloom. That inquiry is expected to finish Sept. 30, but Bloom said yesterday that he intends to ask for an extension to his deadline. He said he has had an office on campus for only 10 days and has just begun his interviews. Bloom said he will study "all the circumstances surrounding her death, with emphasis on her relationship with McGill (and) what lessons can be learned." DOB 19940713 UPDATE 960708 NDATE 19940712 NUPDATE 19960708 ========== END OF DOCUMENT ========== IDNUMBER 199405300060 BASNUM 2005060 PAPER Montreal Gazette DATE 940530 PDATE Monday, May 30, 1994 EDITION Final SECTION Editorial/Op-Ed PAGE B3 LENGTH 1047 words LKW SUICIDE MEDICAL RESEARCH SCIENTIFIC ETHICS MCGILL UNIVERSITY HEADLINE Agonizing case; Sergent story was not based on anonymous letter BYLINE ROBERT WALKER SOURCE GAZETTE Few of the people in the newsroom of The Gazette will ever forget the shock and grief they felt when they learned on April 12 that Justine Sergent and her husband Yves had killed themselves. Several days before the double suicide, the fortunes of The Gazette and of Justine Sergent had become entwined. The newspaper received an anonymous letter dated April 3, a vicious attack on Dr. Sergent. She was a brilliant, 42-year-old scientist at the Montreal Neurological Institute and a professor of neurology and neurosurgery at McGill University. The letter alleged, among other things, that colleagues "had long suspected (Dr. Sergent) of scientific fraud." The letter was signed simply, "A member of the Montreal academic community." The anonymous writer indicated that he or she had sent copies of the letter to nine people, including department heads at McGill, the heads of fundgranting institutions and the editor of the professional journal Science. This almost certainly meant that dozens of people had seen or at least were aware of the letter. On Saturday, April 9, The Gazette published a 14-inch story on Page A3 that set the record straight. The story said Dr. Sergent had been reprimanded in January 1993 on a purely procedural, technical matter, which had nothing to do with the validity of her research or the safety of her human test subjects. In any case, as the story said, she was in the process of appealing the reprimand. Dr. Sergent was quoted extensively. So were officials at McGill and the Neuro. The story pointed out that a joint statement on April 8 from the two institutions said that "none of the facts suggested scientific fraud." The story mentioned the anonymous letter only once and did not quote one word of it. In other words, contrary to what you might have heard on a few radio stations, The Gazette did not "publish an anonymous letter." (No responsible newspaper would dream of publishing such a letter.) We did not publish a story "based on an anonymous letter." Did the opposite We did almost exactly the opposite. We demolished the malicious gossip of the letter, which was merely a starting point - a tip that might be worth checking. The story was based entirely on our own investigation and what we learned from credible people. But why do we take any action on anonymous letters? We usually don't. Newspapers receive them all the time and nearly always throw them on the floor. Typically, they are semi-literate scrawls from fanatics. The letter attacking Dr. Sergent was literate, three pages of clean, singlespaced typing, from someone who obviously knew something about life at the Neuro. (But not everything. The writer apparently did not know about the reprimand in 1993.) Reporters and editors hear tips constantly, some of them from anonymous sources. The newsroom people have to decide whether a given tip is worth the time and effort that will be needed to check it. Sometimes we check a tip and find nothing worth publishing. Sometimes we find a newsworthy story such as the one about Dr. Sergent - not earth-shaking, not worth the front page, but information of legitimate public concern. In a letter to a reader on April 29, Joan Fraser, the editor of The Gazette, observed that she personally had decided to look into the letter about Dr. Sergent. Following is a passage from Miss Fraser's letter: "Dr. Sergent was a world-famous researcher. She had received very large sums of public money to conduct her research, in a publicly funded institution of higher education. To that extent, she was not a private person in her professional life. "Furthermore, the subjects of her work were human and one of her tools was radioactive isotopes. And McGill University is an important part of the Montreal community. All of these things made it impossible for us simply to ignore the story." Bodies found Which leaves us with the agonizing, probably unanswerable question of why the Sergents committed suicide. Their bodies were not found until Tuesday, April 12, but police believe they died on Sunday, April 10, the day after the story appeared in The Gazette. The man who wrote the story was John Kalbfleisch, a highly experienced reporter and editor, who specializes in science, higher education and related areas. He told me last week that he spoke by telephone to Dr. Sergent on the Friday night before the story appeared. Mr. Kalbfleisch said she seemed composed and matter-of-fact, but was emphatic and vigorous in defending her points of view - particularly her opinion that the reprimand had not been justified. He quoted her as saying, "It's a technical dispute, only that. It's now a matter for arbitration." Some friends of the Sergents have suggested that she was shocked on Saturday morning because she had not expected The Gazette to print anything. I asked Mr. Kalbfleisch if she seemed to be unaware that we would run a story. "For example," I asked, "did she try to persuade you not to write anything? Perhaps on the ground that a reprimand normally is kept confidential?" "No, not at all," he replied. "Maybe I missed something, but she seemed to me to understand that I was asking all those questions for the purpose of writing a news story." The people in the newsroom at The Gazette, like those of the Montreal academic community, are still shaken and heartsick at her suicide. Nevertheless, the reporters and editors remain convinced that our action was perfectly ethical. Let me give the last word to Miss Fraser. This is a second passage from her letter of April 29: "One of the reasons why constitutions guarantee the freedom of the press is that we have a duty to report upon problems that arise in great public institutions. We try to do that job as fairly as we can, but it does have to he done." If you have a question, comment or complaint about fairness or accuracy of news coverage in The Gazette, write to the ombudsman, Robert Walker, at 250 St. Antoine St. W., Montreal H2Y 3R7, or telephone 987-2560. If you leave a telephone message or write a letter, please if possible give a phone number where you can be reached during the day. our fax number is 987-2399. DOB 19940531 UPDATE 960708 NDATE 19940530 NUPDATE 19960708 ========== END OF DOCUMENT ========== IDNUMBER 199404290063 BASNUM 1989563 PAPER Montreal Gazette DATE 940429 PDATE Friday, April 29, 1994 EDITION Final SECTION Editorial/Op-Ed PAGE B2 LENGTH 370 words STOTYPE LETTER HEADLINE Researcher broke rules, was not fraud SOURCE GAZETTE I am angered and disgusted by the lack of both judgment and integrity exercised by The Gazette in its coverage of the Dr. Justine Sergent incident. The Gazette brought attention to Dr. Sergent's infringement of McGill University ethics committee rules under the alarming headline "Researcher disciplined by McGill for breaking rules." I refer to this headline as alarming, because it immediately gave me the impression that another researcher such as Dr. Roger Poisson, who intentionally falsified patient records in his research, had been discovered in Montreal. Indeed, the article states that The Gazette's attention was drawn to the Sergent incident by an anonymous letter seeking to draw parallels between Dr. Sergent's case and Dr. Poisson's. However, nothing in the article led me to conclude that Dr. Sergent's alleged violations of McGill ethics committee rules was comparable to the misconduct displayed by Dr. Poisson. Dr. Sergent's subjects were never placed at risk in her experiments, and she never deceived fellow researchers regarding her results. I therefore found the headline grossly misleading. The headline was doubly infuriating because The Gazette's implicit analogy between Dr. Sergent and Dr. Poisson diminished the seriousness of Dr. Poisson's misconduct, which potentially harmed some of his patients, and almost ruined some of North America's most important studies for breast-cancer patients. I was further shocked and saddened to learn that Dr. Sergent committed suicide with her husband after the appearance of The Gazette article. Although the appearance of the article alone probably did not lead Dr. Sergent to take her life, the proximity between the two events is left staring us all in the face. It appeared from the article that Dr. Sergent was already under a great deal of stress; yet at this time The Gazette's headline likened her predicament to Dr. Poisson's. I cannot help but believe that The Gazette's article unjustly added to the pain and distress that finally led Dr. Sergent to commit suicide. The Gazette's expression of distress over Dr. Sergent's suicide is not enough to absolve the paper of its deplorable behavior in this tragic incident. Dr. Sergent did not deserve to be held up in the public eye to seem to be a fraudulent researcher comparable to Dr. Poisson. VIVIAN HAMILTON Montreal DOB 19940430 UPDATE 960708 NDATE 19940429 NUPDATE 19960708 ========== END OF DOCUMENT ========== IDNUMBER 199404210109 RA= 1985609 PAPER Montreal Gazette DATE 940421 PDATE Thursday, April 21, 1994 EDITION Final SECTION News PAGE A3 LENGTH 645 words LKW MEDICAL ETHICS SUICIDE INQUIRIES MCGILL, UNIVERSITY MONTREAL NEUROLOGICAL INSTITUTE HEADLINE McGill sets up two inquiries in Sergent affair BYLINE JOHN KALBFLEISCH SOURCE GAZETTE McGill University is setting up two separate inquiries following the death of Justine Sergent last week. Sergent was a researcher in neuropsychology at the Montreal Neurological Institute, a McGill affiliate. Together with her husband, Yves, she committed suicide after a story in The Gazette described circumstances surrounding a reprimand she received from the university in January 1993 for conducting experiments without ethics committee approval. One inquiry, to last two or three months, will be a scientific audit of her work. It will be conducted by Dr. Pierre Bois, a past president of the Medical Research Council of Canada and formerly dean of medicine at the Universite de Montreal, and Dr. Marcus Raichle of Washington University in St. Louis, a recognized authority in positron emission tomography, a technique central to Sergent's experiments. The other inquiry, headed by Caspar Bloom, batonnier of the Montreal bar, will examine McGill's internal procedures, specifically in relation to Sergent's career. Bloom's inquiry, expected to take three months, will start in may when his term as batonnier ends. The reports of both inquiries are to be made public. At a service for Sergent and her husband Tuesday at St. Albert le Grand Church, neuropsychologist Yves Joanette of the Universite de Montreal said she was a scientist respected as were few others in Canada, indeed in the world. Sergent asked for audit "She was completely dedicated to her research," he said. Sergent had in fact asked McGill to conduct a scientific audit shortly before her reprimand became public knowledge earlier this month. At the time, she told The Gazette that there was nothing questionable about her science, and Dr. Richard Cruess, McGill's dean of medicine, said he seriously doubted the audit would reveal anything untoward. Positron emission tomography is a well-established procedure in which radioactive isotopes enable researchers to plot how the brain handles certain functions. Sergent told The Gazette she believed the ethics committee approval she obtained for testing subjects' reactions to one sort of stimulus, human faces, extended to precisely the same sort of experiment using another stimulus, musical notation. She added that her subjects gave fully informed consent to being tested and that their health was in no way compromised, positions with which McGill concurs. Cruess emphasized that Bloom will have access to all relevant documents, including confidential ones, and will be free to interview a broad spectrum of people. Dr. Peter Fox, director of the research imaging centre at the University of Texas Health Science Centre and a researcher in Sergent's field, drew attention in The Gazette Tuesday to several difficulties Sergent was facing. Felt singled out He mentioned gender equality, the fact that Sergent, though part of the medical faculty, had been trained in psychology, her struggle for professional respect in an institution where she had once been a student, and personality conflicts. "She felt singled out for criticism," Fox told The Gazette in a separate interview. "She lived for her science. She wouldn't be likely to give up a struggle, but would pursue it as a matter of honor. "I regard her act not as one of despair but of outrage." The suggestion of sex discrimination against woman researchers at the university came as no surprise to one McGill neuroscientist contacted by The Gazette. "The climate is inhospitable to female scientists," she said. "Unfortunately, there aren't many jobs elsewhere, so women grumble but feel that they can't move." Another neuroscientist referred to an old-world attitude in Montreal in which science is seen as essentially a male domain. "It was clear to many of us that Justine would not take a back seat to anyone, either as a scientist or as a woman," he said. Cruess rejected the suggestion of sex discrimination. "I can absolutely deny even a hint of that in this case," he said. "Her success in getting funding, in pursuing her research, is against that suggestion." DOB 19940421 UPDATE 960708 NDATE 19940421 NUPDATE 19960708 ========== END OF DOCUMENT ========== Wednesday, July 5, 2000 1:00 PM IDNUMBER 199404200099 BASNUM 1985099 PAPER Montreal Gazette DATE 940420 PDATE Wednesday, April 20, 1994 EDITION Final SECTION Editorial/Op-Ed PAGE B3 LENGTH 501 words STOTYPE COLUMN COLUMN OPINION LKW SUICIDE MEDICAL RESEARCH ETHICS HEADLINE Tragic consequences; Anonymous letter about researcher was a disgrace BYLINE MARTIN ARGUIN; S YLV IE BELLEVILLE; DANIEL BUB; GILLES CTIARPENET; HOWARD CHERTKOW; YVES JOANETTE; MARYSE LASSONDE; ANDRE ROCH LECOURS; ISA13ELLE PERETZ; BERNADETTE SKA; PATRICK VINAY; HARRY WHITAKER; JOHN MARSHALL; ESTHER STRAUSS SOURCE (Freelance) This opinion was submitted by a group of Montreal neuropsychologists and other doctors including Martin Arguin, Sylvie Belleville, Daniel Bub, Gilles Charpenet, Howard Chertkow, Yves Joanette, Maryse Lassonde, Andre Roch Lecours, Isabelle Peretz, Bernadette Ska, Patrick Vinay, Harry Whitaker, John Marshall and Esther Strauss. On Tuesday, April 12, a fellow neuropsychologist, Justine Sergent, was found dead along with her husband. According to what is known at this point, the suicide followed an article published in the April 9 issue of The Gazette. The article reported, among other things, that an anonymous letter received by The Gazette cast doubt on the scientific and ethical integrity of her work. Those allegations were responded to in the article by Dr. Richard Cruess, McGill's dean of medicine, and Dr. Richard Murphy, the director of the Montreal Neurological Institute. As part of the Montreal neuropsychological and scientific community, we would like to express our revulsion at the writing of an anonymous letter as a means of putting allegations into the public sphere. We are all concerned that a newspaper can publish such allegations without waiting for the results of an official investigation. Any of us could in fact be victimized by such anonymous allegations merely by having them exist in print. But over and above our sadness and our indignation, the neuropsychological community of Montreal has without a doubt lost one of its most world-renowned figures. Over the last decade or so, as a grantee of the Canadian Medical Research Council of Canada - by which she was attributed the prestigious title of "scientist" - and of many other funding agencies, Dr. Sergent was certainly among the most productive and widely read neuropsychologists in Canada and one of the major figures of the international co mmu nity. Dr. Sergent was highly intelligent, insightful as well as most original and creative in her work. She was totally devoted to her research activities. Her multiple contributions to the field, both in terms of empirical facts and theories, were read by the scientific community around the world. She was known for her scientific contributions which, at times, were deliberately pro vocative in order to generate collegial reactions. Among her contributions, she submitted to the community an original approach to the origins of the functional lateralization of the brain, based on some of the elementary characteristics of visual stimuli, an hypothesis which was known throughout as the Sergent hypothesis. Recently, she had recourse to the most powerful brain-imaging techniques in order to unveil the cerebrum's mysteries. Dr. Sergent's numerous publications were to be found in the most widely respected scientific journals, including Science and Nature. They are widely considered to represent a very high standard of sophistication in the field of neuropsychology and her work has had wide influence. We profoundly regret the events that were at the origins of the desperate choice of our colleague. On her demise, lies a profound message to the scientific milieu and the media. We mourn the passing of our colleague and the unfinished opus of her contribution. DOB 19940420 UPDATE 960708 NDATE 19940420 NUPDATE 19960708 ========== END OF DOCUMENT ========== IDNUMBER 199404190008 BASNUM 1984508 PAPER Montreal Gazette DATE 940419 PDATE Tuesday, April 19, 1994 EDITION Final SECTION Editorial/Op-Ed PAGE B3 LENGTH 1002 words STOTYPE PROFILE; COLUMN COLUMN PETER T. FOX LKW SUICIDE MEDICAL RESEARCH ETHICS HEADLINE WHY DID A BRILLIANT RESEARCHER CHOOSE TO TAKE HER OWN LIFE? BYLINE PETER T. FOX SOURCE (Freelance) Reports of the self-inflicted deaths of Professor Justine Sergent and her husband, Yves Sergent, have shocked and puzzled the city of Montreal and the scientific community at large. This desperate action was precipitated by an anonymous letter from a colleague accusing Sergent of scientific fraud (The Gazette, April 9). Neither the report of that accusation nor Wednesday's report of the dual suicide (April 13) begin to resolve the questions surrounding this tragedy. Who was Justine Sergent? Was she guilty of scientific fraud? If not, why did she choose to end her life? As a scientific colleague, a collaborator, and a personal friend of Justine and Yves Sergent, I offer my answers, admittedly incomplete, to these troubling questions. Sergent received her undergraduate and doctoral degrees in psychology from McGill University. At McGill, as elsewhere, only truly outstanding students are offered academic posts; Sergent was such a student. Appointed to the faculty, Sergent progressed rapidly through the academic ranks. To further her studies, she visited often with outstanding scientists in other countries, establishing long-standing, highly productive collaborations. In the past decade, Sergent published extensively, typically in well-respected international journals. Sergent's work centred on the functional differences between the two cerebral hemispheres. Most recently, Sergent had focused on the mental processes underlying object recognition (especially recognition of human faces) and music. In these areas, Sergent was a world authority. At the time of her death, Sergent was under review for the final step up the academic ladder: full professor at one of the world's most eminent institutions. The fundamental criterion for such nomination is internationl stature. International reputation is not easily won. Yet, in every sense of the phrase, Sergent was internationally acclaimed. What are we to make of an anonymous accusation that "Sergent has built a scientific career on the basis of what colleagues at McGill and elsewhere have long suspected was scientific fraud?', This is a deliberate and outrageous falsehood. I have attended many of Sergent's lectures. I have engaged in discussions of her work with colleagues from around the world. As an active collaborator with scientists at the Montreal Neurological Institute, I have viewed first-hand the workings of its laboratories. Never once have I received the slightest indication that any scientist within or outside of McGill suspected Sergent. of falsifying data. Colleagues with whom I have spoken over the past few days are shocked and outraged by this accusation, just as they are grief-stricken by the tragedy of her death. The international scientific community supports McGill University officials in giving no credence to this accusation. Why, then, did Sergent not face down her accuser and vindicate herself? Why isn't her action an admission of guilt? Sergent was more than a brilliant intellect; she was utterly dedicated to science. Childless and having no family on this continent other than her husband, she lived for her work. The standards of excellence that she set for herself surpassed the reach of all but the very finest of scientists. Little wonder that she was a woman of strict honor and ferocious independence, prizing both her reputation and her scientific freedom. The accusation of fraud struck at the heart of her concept of selfworth, clearly the intent of her accuser. Nevertheless, an isolated accusation, however grievous, is not a sufficient provocation to make a rational person choose to die. What else had transpired? Academic success is a Darwinian process: only the strong survive. The competition is intense and highly stressful, In this competition, being a member of the majority is a distinct advantage. As remains true in many fields, success in academics is less common for women. While psychology (the field in which she trained) is approaching gender equality, neurology and neurosurgery (the field in which she worked) remain male- dominated. Similarly, Sergent's PhD degree was an anomaly in a medical department and could only have made her situation less certain and more stressful. Finally, the path is hardest for those who rise from within. Marks of respect are afforded only grudgingly to one's former students. Sergent was justly proud of her accomplishments and consummately professional in her bearing. As was her due, she would not tolerate personal disrespect in the workplace. Sergent had privately acknowledged for years that interactions with some colleagues at the MNI were very problematic. The disciplinary action by the MNI ethics committee, Sergent believed, was based on personal grievances, not on scientific misconduct. These issues hopefully, will be fully explored by McGill authorities. Regardless of the outcome of such investigations, I believe that Sergent was equally a casualty of her own uncompromising standards of excellence and of an inhospitable work environment. I spoke on the telephone with Justine on Saturday evening, about 36 hours before her death. The auditors, she said, had just left her laboratory. If Sergent had wished to conceal a fraud, she could have destroyed the data. Instead, she requested an audit and opened her laboratory - her last professional act. As we spoke, she expressed outrage that her scientific integrity was called into question. She also voiced bitter disappointment that she had for many months needed legal representation to interact with the university to which she had dedicated her entire adult life. I encouraged her to leave Montreal, at least for a time. This was out of the question. McGill University and the MNI were her life ... and her death. The death of Justine Sergent is a tragedy. Cognitive neuroscience, a young and fragile field, has lost a leader. Sergent was at the forefront, showing us the way. Service to the scientific community - as a journal editor, a grant reviewer, a funding-foundation program officer, a scientific advisor - was offered with a generosity seldom seen. The neuroscience community is grief stricken. We have lost a rare colleague and a dear friend. * Peter T. Fox is a professor in the department of radiology, medicine (neurology) and psychiatry and director of the research imaging centre at the University of Texas Health Science Centre in San Antonio

. DOB 19940420 UPDATE 960708 NDATE 19940419 NUPDATE 19960708 ========== END OF DOCUMENT ========== IDNUMBER 199404140095 BASNUM 1982095 PAPER Montreal Gazette DATE 940414 PDATE Thursday, April 14, 1994 EDITION Final SECTION News PAGE Al/FRONT LENGTH 249 words LKW GAZETTE MTL SUICIDE RESEARCH SCIENTIFIC ETHICS MCGILL UNIVERSITY HEADLINE To our readers SOURCE GAZETTE The Gazette was deeply distressed to learn of the deaths of Professor Justine Sergent, a researcher at the Montreal Neurological Institute, and her husband, Yves. The newspaper's editors and reporters were shocked by the couple's apparent suicide. As The Gazette reported last Saturday, Dr. Sergent was reprimanded by McGill University, with which the neurological institute is affiliated, after she conducted certain experiments on human subjects without ethics committee approval. All parties agree th At Dr. Sergent's insistence, the reprimand was submitted to arbitration, and that process was continuing. In addition, McGill had agreed to her request that an independent scientific audit be conducted on her work. The dispute was the subject of a detailed, anonymous letter attacking Dr. Sergent that was addressed this month to the editor of The Gazette, as well as to the heads of the Medical Research Council of Canada, the Fonds de la Recherche en Sante du Quebec, Science magazine and six senior administrators of the university. The Gazette, as was its journalistic responsibility, investigated the letter's allegations with the parties directly concerned - McGill University and Dr. Sergent. Both presented their positions coherently and without rancor, and these were at the core of The Gazette's report on Saturday. McGill and Dr. Sergent readily co-operated with The Gazette's requests for information. At no time did Dr. Sergent express any undue distress. The Gazette is profoundly distressed by this week's events, and extends its sympathy to the families of Dr. Sergent and her husband. - The editors DOB 19940415 UPDATE 960708 NDATE 19940414 NUPDATE 19960708 ========== END OF DOCUMENT ========== IDNUMBER 199404130052 BASNUM 1981552 PAPER Montreal Gazette DATE 940413 PDATE Wednesday, April 13, 1994 EDITION Final SECTION News PAGE A3 LENGTH 461 words LKW MTL SUICIDE MONTREAL NEUROLOGICAL INSTITUTE RESEARCH SCIENTIFIC ETHICS AUDIT HEADLINE Researcher, husband commit suicide; Bodies found after woman missed meeting over experiment dispute BYLINE JOHN KALBFLEISCH SOURCE GAZETTE A researcher at the Montreal Neurological Institute and her husband were found dead yesterday morning in the garage beneath their home, apparently the victims of carbon-monoxide poisoning. Police were asked to look for Justine Sergent after she failed to show up for an important meeting Monday morning focusing on a continuing dispute she has had with McGill University over some of her experiments. As described in a Gazette story last Saturday, Sergent was appealing a January 1993 reprimand by the university for conducting certain experiments on people without ethics-committee approval. While an autopsy is to be held this morning, Montreal Urban Community police say all signs indicate Sergent and her husband, Yves Sergent, committed suicide. Their bodies were discovered in their car, parked in the closed garage beneath their home. A hose led from the car's exhaust pipe to the passenger compartment and the car's engine was still running. Squad cars and ambulances from north-end Stationl crowded around the rear alley leading to the garage of the modest duplex where the bodies were discovered. About 30 passers-by gathered around the small police cordon to catch a glimpse of what had happened. Concerned by Sergent's failure to appear at the Monday meeting, the university later that day sent an official to her home. No one answered the door and the bodies were discovered only after police were notified. "A matter that was essentially an internal dispute involving her and her work environment was blown way out of proportion, with the consequences we know today," Eric Maldoff, Sergent's lawyer, said. Sergent's experiments at the neurological institute, a McGill affiliate, used a well-established procedure known as positron emission tomography to map certain brain processes. In an interview Friday, Sergent told The Gazette she believed that permission granted for testing her subjects' reaction to one sort of stimulus, images of human faces, applied to further experiments using precisely the same experimental procedures, but with a different stimulus, musical notation. Sergent said there was nothing bizarre or improper about the experiments and that the subjects' health was in no way compromised. McGill has readily agreed with these two points all along. The dispute, though regarded as serious, was entirely a technical one. In fact, it had moved to arbitration, in which Sergent was maintaining that the reprimand and the McGill investigation leading up to it were unfair. McGill had agreed to Sergent's request that an independent audit be set up to establish the integrity of her work and Maldoff said that in order to establish her scientific legacy he hoped the audit would proceed. Principal David Johnston of McGill confirmed yesterday there was no intention of suspending the audit. "The results will be released when it is completed within the next two or three months," he said. DOB 19940414 UPDATE 960708 NDATE 19940413 NUPDATE 19960708 ========== END OF DOCUMENT ========== IDNUMBER 199404090097 13ASNUM 1979597 PAPER Montreal Gazette DATE 940409 PDATE Saturday, April 9, 1994 EDITION Final SECTION News PAGE A3 LENGTH 574 words Ly1W MCGILL UNIVERSITY MEDICAL SCIENTIFIC RESEARCH ETHICS HEADLINE Researcher disciplined by McGill for breaking rules BYLINE JOHN KALBFLEISCH SOURCE GAZETTE McGill University has taken disciplinary measures against a researcher at the Montreal Neurological Institute who broke the university's rules during some of her experiments. Dr. Justine Sergent, 42, a professor of neurology and neurosurgery, failed to get ethics-committee approval to use a procedure called positron emission tomography. Sergent insists her subjects were never at risk and her work has not been negated by the reprimand. "It was always conducted in an ethical and proper manner," she said yesterday. "That my data are not valid has never been at issue. The safety of the subjects who volunteered isn't an issue, either." The Neuro is a McGill affiliate. The complaint against Sergent was laid in July 1992 and an investigation was launched shortly thereafter. It led to an official reprimand for academic misconduct by McGill principal David Johnston in January 1993. Sergent waited until last summer before appealing the reprimand. Arbitration proceedings have begun. In Sergent's experiments, radioactive isotopes were used to explore how the human brain functions when volunteer pianists read sheet music and translated that information to a keyboard. Dr. Richard Cruess, McGill's dean of medicine, agreed that Sergent got proper consent from her subjects and that nothing has been found questionable in the actual science she practiced. An anonymous letter received by McGill and The Gazette this week seeks to draw parallels between Sergent's case and the fraudulent practices of Dr. Roger Poisson of St. Luc Hospital, who altered patient records in his breast- cancer research. A joint response yesterday by Cruess and Dr. Richard Murphy, the Neuro's director, says, "While the investigation carried out was not mandated to look into the issue of fraud in either fabricating or interpreting data, it should be pointed out that none of the facts suggested scientific fraud. "All subject consent forms were in order, and specific questions about the validity of data were constantly answered in the affirmative." Their statement deplored the anonymous accusations that could harm someone's career. Positron emission tomography is a well-established procedure in modern neurobiological research. Radioactive isotopes injected into the brain enable researchers to track how the brain functions during certain activities. Sergent obtained ethics-committee approval to use the procedure in her investigation of how the brain is involved in recognizing human faces. But she didn't seek approval for her work on music, believing it simply to be an extension of the work on faces. "I believe the approval covered the use of precisely the same technique for the music experiment," she said. "Everything else was the same. The only things that changed were the stimuli on the screen. The subjects were simply shown musical notation instead of faces. "It's a technical dispute, only that," she said. "It's now a matter for arbitration." Sergent has invited McGill to investigate the way she actually conducted her experiments, and Cruess confirmed that a scientific audit has been launched. He added, however, that nothing leads him to expect irregularities will be found. The original McGill investigation also found that Sergent had flouted the rules by altering the telephone numbers she kept in the written files of some of her subjects. She maintains this was done to shield the phone numbers from rival researchers, but adds that the true numbers were never changed in her computerized files. That matter is also the subject of arbitration. Sergent said that apart from the reprimand, she has not been disciplined in any way. She continues her work at the Neuro. DOB 19940410 UPDATE 960708 NDATE 19940409 NUPDATE 19960708 ========== END OF DOCUMENT ==========